<International Circulation>: Could you share with us the latest on acute decompensated heart failure?

 《国际循环》：您能同我们分享一下，最新的急性失代偿心力衰竭的进展么？

    Dr Adams:  Acute heart failure is really bedeviling us. There are over a million hospitalizations a year and we still see an increase in hospitalization. Heart failure advances as age advances so the aging of the population is driving up these decompensated cases. When you look at outcomes in the hospital and during follow-up， it is very poor in this sub-group of patients. In fact， it is one of the reasons why we are interested in biomarker guided therapy as this population has proven so difficult to treat. Our message about acute heart failure is we need more research and we need more investigation. The epidemiology says there is a huge economic burden， close to