<International Circulation>: For what proportion of CLI patients is standard revascularization not an option and for whom these new therapies will be very significant?
   《国际循环》：至于患CLI患者的标准的血管再通的比率是不是随意的？对他们来说新的治疗将会使显著的吗？

    Prof. Emmerich: We are talking about a very small percentage of patients with CLI， as the first thing to do is perform revascularization by angiography or bypass surgery， so it is less than 30% of presenting patients. The inclusion of these patients in these trials is rather difficult. Most of the time， these patients are going through the surgical ward and attempting difficult distal bypass surgery with the risk of occlusion and after that they are going through to amputation. The difficulty of recruitment is that we need to get these patients at an early stage before the available options are no longer performable.
    Emmeric教授：我们正在谈论的是小部分的CLI患者，最首要的事情是通过血管造影或外科旁路分流术实行血管再通，这至少包括现有病人的30%。这些患者处在这些试验当中是相当困难的，大多数时候，这些患者是通过外科手术，尝试困难的远端旁路分流手术，这是冒着血管闭塞和闭塞后将被截肢的危险的。恢复健康的困难是我们需要发现患者处在早期阶段，但在有效的选择治疗之前是不可能完成的。